NOVEL RECURRENT CHROMOSOMAL ABERRATIONS DETECTED IN CLONAL PLASMA CELLS OF LIGHT CHAIN AMYLOIDOSIS PATIENTS SHOW POTENTIAL ADVERSE PROGNOSTIC EFFECT: FIRST RESULTS FROM A GENOME-WIDE COPY NUMBER ARRAY ANALYSIS

Immunoglobulin light chain (AL) amyloidosis is a rare plasma cell dyscrasia characterized by the deposition of abnormal amyloid fibrils in multiple organs, thus impairing their function.In the largest cohort studied up to now of 118 CD138-purified plasma cell samples from previously untreated immunoglobulin light chain amyloidosis patients, we asse

tsc apparel houston The study sought to ascertain the magnitude of the external tax compliance costs incurred by SMEs in Ghana from the perspective of the tax professionals who provide the service.Tax professional firms were selected from the Institute of Chartered Accountants and the Chartered Institute of Taxation for the study.The study distingu

ABSTRACT Objective: To evaluate the seropositivity rate of rapid tests for HIV, syphilis and hepatitis B and C among transvestites and transgender women (transfeminine persons) inmates in the metropolitan region of Rio de Janeiro, analyzing the results based on sociodemographic, prison profile and access to health technologies to prevent sexually t

Aiming at the current situation of lack of environment and equipment in radar training, a radar operation training method based on the combination of virtual and real is proposed.Firstly, the connotation of the concept of virtual-real combination is analyzed.Secondly, the interaction dragon dusk sunglasses methods of combining physical radar and vi

Genome editing is a set of techniques for introducing targeted changes in genomes.It may be achieved by enzymes collectively called site-directed nucleases (SDN).Site-specificity of SDNs is provided either by the DNA binding fsu headband domain of the protein molecule itself or by RNA molecule(s) that direct SDN to a specific site in the genome.In